Article-Journal

Development of a humanized anti-FABP4 monoclonal antibody for potential treatment of breast cancer

Jiaqing Hao, Rong Jin, Yanmei Yi, Xingshan Jiang, Jianyu Yu, Zhen Xu, Nicholas J Schnicker, Michael S Chimenti, Sonia L Sugg, Bing Li

Effects of 28-day nose-only inhalation of PCB52 (2, 2′, 5, 5′-Tetrachlorobiphenyl) on the brain transcriptome

Amanda J Bullert, Hui Wang, Morgan J Linahon, Michael S Chimenti, Andrea Adamcakova-Dodd, Xueshu Li, Michael E Dailey, Aloysius J Klingelhutz, James a Ankrum, Hanna E Stevens, Others

Modulation of the Immunological Milieu in Acute Aneurysmal Subarachnoid Hemorrhage: The Potential Role of Monocytes Through CXCL10 Secretion

Sebastian Sanchez, Michael S Chimenti, Yongjun Lu, Elena Sagues, Andres Gudino, Carlos Dier, David Hasan, Edgar a Samaniego

Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57

Waheed Awotoye, Ligiane a Machado-Paula, Luke Hovey, Henry Keen, Michael Chimenti, Benjamin Darbro, Shareef Dabdoub, James C Thomas, Jeffrey C Murray, Shankar Rengasamy Venugopalan, Others

Spatial differences in gene expression across the dorsal raphe nucleus in a model of early Alzheimer's disease

Map2k3os may serve regulatory roles relevant for tau phosphorylation and warrants further investigation to characterize its interactions. Overall, this report demonstrates the power of large-scale spatial transcriptomics technologies, while underscoring the need for convergent-data validation to overcome their limitations.

Louis J Kolling, Michael S Chimenti, Catherine a Marcinkiewcz

Spatial differences in gene expression across the dorsal raphe nucleus in a model of early Alzheimer's disease

Upregulation of fatty acid synthesis genes in the livers of adolescent female rats caused by inhalation exposure to PCB52 (2, 2′, 5, 5′-Tetrachlorobiphenyl)

Brynn Kyleakin Helm-Kwasny, Amanda Bullert, Hui Wang, Michael S Chimenti, Andrea Adamcakova-Dodd, Xuefang Jing, Xueshu Li, David K Meyerholz, Peter S Thorne, Hans-Joachim Lehmler, Others

Whole genome sequencing of a family with autosomal dominant features within the oculoauriculovertebral spectrum

Aline L Petrin, LAM Machado-Paula, A Hinkle, Luke Hovey, Waheed Awotoye, M Chimenti, B Darbro, Lucilene a Ribeiro-Bicudo, Shareef M Dabdoub, T Peter, Others

CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression

Jordan L Kohlmeyer, Joshua J Lingo, Courtney a Kaemmer, Amanda Scherer, Akshaya Warrier, Ellen Voigt, Juan a Raygoza Garay, Gavin R McGivney, Qierra R Brockman, Amy Tang, Others

Hydroxylation markedly alters how the polychlorinated biphenyl (PCB) congener, PCB52, affects gene expression in human preadipocytes

Francoise a Gourronc, Michael S Chimenti, Hans-Joachim Lehmler, James a Ankrum, Aloysius J Klingelhutz

Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis

Jiaqing Hao, Jianyu Yu, Matthew S Yorek, Chi-Li Yu, R Marshall Pope, Michael S Chimenti, Yiqin Xiong, Aloysius Klingelhutz, Ali Jabbari, Bing Li